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Source: 2014 Surgeon General's Report, Table 12.4, page 660 Evidence-based studies implicate smoking as a major risk factor for cancers , including: Lung cancer Bladder cancer Laryngealcancer Oral cancer Cervical cancer Pancreatic cancer Esophageal cancer Stomach cancer Kidney cancer Leukemia Smoking is recognized as a leading risk factor for cardiovascular diseases including abdominal aortic aneurysm, atherosclerosis, cerebrovascular disease and coronary heart disease